Botswana Travel Health Guide
Moderate risk
Botswana carries a CDC Level 1 travel health notice. Malaria risk exists in certain areas of Botswana. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B. Yellow fever vaccine is not needed if traveling directly from the US, but is required if you're coming from a country with yellow fever risk or have long layovers in such countries.
Overall risk
Moderate risk
Malaria
Present
Best time to visit
Year-round
Recommended vaccines
Routine vaccines
Make sure all your routine vaccines are up to date, including chickenpox, tetanus, flu, MMR, polio, and shingles vaccines.
COVID-19
Stay up to date with your COVID-19 vaccines before traveling.
Hepatitis A
Get hepatitis A vaccine if you haven't been vaccinated. Infants 6-11 months also need vaccination. Special protocols apply for older adults and those with health conditions.
Hepatitis B
Get hepatitis B vaccine if you haven't been vaccinated, regardless of your age.
Measles
Measles cases are increasing worldwide. Make sure you're fully vaccinated with MMR vaccine at least 2 weeks before travel. Infants 6-11 months need an early dose.
Typhoid
Typhoid vaccination is recommended for most travelers, especially if you're staying with friends/family or visiting smaller cities and rural areas.
Rabies
Consider rabies vaccination if you'll be around animals or in remote areas. Rabies is present in dogs and wildlife in Botswana, and treatment may only be available in larger medical facilities.
Yellow Fever
Yellow fever vaccine is not needed if traveling directly from the US, but is required if you're coming from a country with yellow fever risk or have long layovers in such countries.
Disease risks
Malaria risk
Malaria is present in this destination. Prophylaxis medication is recommended.
Malaria risk exists in certain areas of Botswana. Take prescription antimalarial medication if visiting high-risk districts. No malaria risk in the capital Gaborone. Chloroquine-resistant malaria is present.
Emergency numbers
Police
999
Medical / Ambulance
997
Fire
998
U.S. Embassy
+267-395-3982
More country guides
Eswatini carries a CDC Level 1 travel health notice. Malaria risk exists in eastern areas of Eswatini bordering Mozambique and South Africa. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B. Yellow fever vaccine is not needed if traveling directly from the US, but is required if you're coming from a country with yellow fever risk or have long layovers in such countries.
Lesotho carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
Namibia carries a CDC Level 1 travel health notice. Malaria risk exists in specific regions of Namibia, primarily caused by P. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B. Yellow fever vaccine is not needed for disease protection in Namibia, but is required for entry if you're coming from a country with yellow fever risk, including airport layovers over 12 hours.
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Build my Trip KitSources: CDC Travelers' Health · WHO International Travel and Health. Last updated 2026-07-31. Health conditions and entry rules change — verify with the CDC, WHO and your destination’s authorities before travel. This page is informational and not a substitute for advice from a travel-medicine provider.