KH flagModerate riskAsia · South-Eastern Asia

Cambodia Travel Health Guide

Moderate risk

Cambodia carries a CDC Level 1 travel health notice. Malaria risk exists primarily in rural and forested areas of Cambodia. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.

Overall risk

Moderate risk

Malaria

Present

Best time to visit

Year-round

Recommended vaccines

Routine vaccines

Make sure all routine vaccines are up to date, including chickenpox, tetanus, flu, MMR, polio, and shingles vaccines.

Recommended

COVID-19

Stay up to date with COVID-19 vaccines before traveling.

Recommended

Hepatitis A

Hepatitis A vaccine is recommended for all travelers to Cambodia who haven't been vaccinated. Even infants 6-11 months should get vaccinated.

Recommended

Hepatitis B

Hepatitis B vaccine is recommended for travelers under 60. Those 60 and older may choose to get vaccinated.

Recommended

Measles

All travelers should be fully vaccinated against measles with MMR vaccine, including infants 6-11 months who need an early dose.

Recommended

Typhoid

Typhoid vaccine is recommended for most travelers to Cambodia, especially if staying with locals or visiting smaller cities and rural areas.

Recommended

Chikungunya

Chikungunya vaccine is generally not recommended. Focus on preventing mosquito bites instead.

Situational

Japanese Encephalitis

Japanese encephalitis vaccine is recommended if you're staying long-term, frequently traveling to the area, or doing outdoor activities in rural areas without proper protection from mosquitoes.

Situational

Rabies

Rabies-infected dogs are common in Cambodia. Consider pre-exposure vaccination if you'll be doing activities that increase animal exposure or might have difficulty getting prompt medical care.

Situational

Yellow Fever

Yellow fever vaccine is not recommended for Cambodia itself, but is required for entry if you're coming from a country with yellow fever risk, including airport layovers over 12 hours.

Situational

Disease risks

Malaria risk

Malaria is present in this destination. Prophylaxis medication is recommended.

Malaria risk exists primarily in rural and forested areas of Cambodia. No risk in major cities like Phnom Penh, Siem Reap, or Angkor Wat. Take antimalarial medication if visiting rural/forested areas.

Emergency numbers

Police

117

Medical / Ambulance

119

Fire

118

U.S. Embassy

+855-23-728-000

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Sources: CDC Travelers' Health · WHO International Travel and Health. Last updated 2026-07-31. Health conditions and entry rules change — verify with the CDC, WHO and your destination’s authorities before travel. This page is informational and not a substitute for advice from a travel-medicine provider.