High riskAfrica · Eastern AfricaComoros Travel Health Guide
High risk
Comoros carries a CDC Level 1 travel health notice. Malaria risk exists throughout Comoros. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
Overall risk
High risk
Malaria
Present
Best time to visit
Year-round
Recommended vaccines
Routine Vaccines
Make sure all your routine vaccines are current before traveling, including flu, MMR, tetanus, and others.
COVID-19
Stay up to date with COVID-19 vaccines before traveling.
Hepatitis A
Hepatitis A vaccine is recommended for all travelers to Comoros age 1 and older. Infants 6-11 months should also get vaccinated.
Hepatitis B
Hepatitis B vaccine is recommended for travelers under 60. Those 60 and older may also consider vaccination.
Measles
Measles vaccination with MMR is essential for all travelers due to rising cases worldwide. Must be vaccinated at least 2 weeks before travel.
Typhoid
Typhoid vaccination is recommended for most travelers, especially if visiting rural areas or staying with friends and relatives.
Cholera
Cholera vaccination may be considered if traveling to the Ngazidja region where there is active transmission. Risk is low for most travelers.
Rabies
Consider rabies vaccination before travel if you'll be around animals or in remote areas. Rabid dogs are common and treatment may be hard to find outside major cities.
Yellow Fever
Yellow fever vaccination is not needed for travel to Comoros and is not required for entry.
Disease risks
Malaria risk
Malaria is present in this destination. Prophylaxis medication is recommended.
Malaria risk exists throughout Comoros. Take prescription antimalarial medication as recommended by your doctor. Start taking it before your trip and continue during and after travel.
Emergency numbers
Police
17
Medical / Ambulance
18
Fire
18
U.S. Embassy
+261-20-23-480-00
More country guides
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BurundiHigh riskBurundi carries a CDC Level 1 travel health notice. Malaria risk exists throughout Burundi year-round. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
DjiboutiHigh riskDjibouti carries a CDC Level 2 travel health notice. Malaria risk exists throughout Djibouti. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B. Yellow fever vaccination not needed for disease protection but required for entry if traveling from countries with yellow fever risk, including airport layovers over 12 hours.
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Build my Trip KitSources: CDC Travelers' Health · WHO International Travel and Health. Last updated 2026-07-31. Health conditions and entry rules change — verify with the CDC, WHO and your destination’s authorities before travel. This page is informational and not a substitute for advice from a travel-medicine provider.