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Eswatini Travel Health Guide

Moderate risk

Eswatini carries a CDC Level 1 travel health notice. Malaria risk exists in eastern areas of Eswatini bordering Mozambique and South Africa. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B. Yellow fever vaccine is not needed if traveling directly from the US, but is required if you're coming from a country with yellow fever risk or have long layovers in such countries.

Overall risk

Moderate risk

Malaria

Present

Best time to visit

Year-round

Recommended vaccines

Routine Vaccines

Make sure all your routine vaccines are up to date, including chickenpox, tetanus, flu, MMR, polio, and shingles vaccines.

Required

COVID-19

Stay up to date with your COVID-19 vaccines before traveling.

Recommended

Hepatitis A

Get vaccinated against Hepatitis A before traveling to Eswatini. Special timing and dosing may apply for infants, older adults, and those with health conditions.

Recommended

Hepatitis B

Get vaccinated against Hepatitis B if you haven't been vaccinated before traveling to Eswatini.

Recommended

Measles

Measles cases are increasing globally. Make sure you're fully vaccinated with MMR vaccine at least 2 weeks before travel. Infants 6-11 months need special early vaccination.

Recommended

Typhoid

Typhoid vaccination is recommended for most travelers to Eswatini, especially if you're staying with local families or visiting smaller towns and rural areas.

Recommended

Rabies

Rabies is present in dogs and wildlife in Eswatini. Consider pre-travel vaccination if you'll be around animals or in remote areas. Rabies vaccines are available throughout the country if needed after exposure.

Situational

Yellow Fever

Yellow fever vaccine is not needed if traveling directly from the US, but is required if you're coming from a country with yellow fever risk or have long layovers in such countries.

Situational

Disease risks

Malaria risk

Malaria is present in this destination. Prophylaxis medication is recommended.

Malaria risk exists in eastern areas of Eswatini bordering Mozambique and South Africa. Take antimalarial medication if visiting these areas. The malaria parasites are resistant to chloroquine.

Emergency numbers

Police

999

Medical / Ambulance

977

Fire

933

U.S. Embassy

+27-12-431-4000

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Sources: CDC Travelers' Health · WHO International Travel and Health. Last updated 2026-07-31. Health conditions and entry rules change — verify with the CDC, WHO and your destination’s authorities before travel. This page is informational and not a substitute for advice from a travel-medicine provider.