Eswatini Travel Health Guide
Moderate risk
Eswatini carries a CDC Level 1 travel health notice. Malaria risk exists in eastern areas of Eswatini bordering Mozambique and South Africa. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B. Yellow fever vaccine is not needed if traveling directly from the US, but is required if you're coming from a country with yellow fever risk or have long layovers in such countries.
Overall risk
Moderate risk
Malaria
Present
Best time to visit
Year-round
Recommended vaccines
Routine Vaccines
Make sure all your routine vaccines are up to date, including chickenpox, tetanus, flu, MMR, polio, and shingles vaccines.
COVID-19
Stay up to date with your COVID-19 vaccines before traveling.
Hepatitis A
Get vaccinated against Hepatitis A before traveling to Eswatini. Special timing and dosing may apply for infants, older adults, and those with health conditions.
Hepatitis B
Get vaccinated against Hepatitis B if you haven't been vaccinated before traveling to Eswatini.
Measles
Measles cases are increasing globally. Make sure you're fully vaccinated with MMR vaccine at least 2 weeks before travel. Infants 6-11 months need special early vaccination.
Typhoid
Typhoid vaccination is recommended for most travelers to Eswatini, especially if you're staying with local families or visiting smaller towns and rural areas.
Rabies
Rabies is present in dogs and wildlife in Eswatini. Consider pre-travel vaccination if you'll be around animals or in remote areas. Rabies vaccines are available throughout the country if needed after exposure.
Yellow Fever
Yellow fever vaccine is not needed if traveling directly from the US, but is required if you're coming from a country with yellow fever risk or have long layovers in such countries.
Disease risks
Malaria risk
Malaria is present in this destination. Prophylaxis medication is recommended.
Malaria risk exists in eastern areas of Eswatini bordering Mozambique and South Africa. Take antimalarial medication if visiting these areas. The malaria parasites are resistant to chloroquine.
Emergency numbers
Police
999
Medical / Ambulance
977
Fire
933
U.S. Embassy
+27-12-431-4000
More country guides
Botswana carries a CDC Level 1 travel health notice. Malaria risk exists in certain areas of Botswana. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B. Yellow fever vaccine is not needed if traveling directly from the US, but is required if you're coming from a country with yellow fever risk or have long layovers in such countries.
Lesotho carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
Namibia carries a CDC Level 1 travel health notice. Malaria risk exists in specific regions of Namibia, primarily caused by P. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B. Yellow fever vaccine is not needed for disease protection in Namibia, but is required for entry if you're coming from a country with yellow fever risk, including airport layovers over 12 hours.
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Build my Trip KitSources: CDC Travelers' Health · WHO International Travel and Health. Last updated 2026-07-31. Health conditions and entry rules change — verify with the CDC, WHO and your destination’s authorities before travel. This page is informational and not a substitute for advice from a travel-medicine provider.