Paraguay Travel Health Guide
Low risk
Paraguay carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B. Yellow fever vaccine is recommended for most areas of Paraguay except Asunción city. Required if arriving from Bolivia, Brazil, Peru, or Venezuela (including layovers >24 hours)
Overall risk
Low risk
Malaria
None
Best time to visit
Year-round
Recommended vaccines
Routine vaccines
Make sure all routine vaccines are up to date including chickenpox, tetanus, flu, MMR, polio, and shingles
COVID-19
Stay up to date with COVID-19 vaccines before traveling
Hepatitis A
Hepatitis A vaccine is recommended for all unvaccinated travelers over 1 year old. Infants 6-11 months should also get vaccinated
Hepatitis B
Hepatitis B vaccine is recommended for unvaccinated travelers under 60. Those 60 and older may consider vaccination
Measles
All travelers should be fully vaccinated with MMR vaccine at least 2 weeks before travel. Infants 6-11 months need an early dose
Typhoid
Typhoid vaccine is recommended for most travelers, especially if visiting rural areas or staying with friends/relatives
Chikungunya
Chikungunya vaccine is generally not recommended. Focus on preventing mosquito bites instead
Rabies
Rabies is found in dogs and wildlife in Paraguay. Consider pre-exposure vaccination if you'll be around animals or in remote areas where treatment may not be readily available
Yellow Fever
Yellow fever vaccine is recommended for most areas of Paraguay except Asunción city. Required if arriving from Bolivia, Brazil, Peru, or Venezuela (including layovers >24 hours)
Disease risks
Traveler's Diarrhea
Parts of Alto Paraná, Amambay, Canindeyú; low risk in Asunción.
Emergency numbers
Police
911
Medical / Ambulance
911
Fire
911
U.S. Embassy
+595-21-213-715
More country guides
Argentina carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
Bolivia carries a CDC Level 2 travel health notice. Malaria risk exists in areas below 2,500m elevation. Key travel vaccines: COVID-19, Chikungunya, Hepatitis A. Required for entry (applies below 2300m)
Brazil carries a CDC Level 1 travel health notice. Malaria risk exists in certain areas of Brazil. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
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Build my Trip KitSources: CDC Travelers' Health · WHO International Travel and Health. Last updated 2026-07-31. Health conditions and entry rules change — verify with the CDC, WHO and your destination’s authorities before travel. This page is informational and not a substitute for advice from a travel-medicine provider.