Puerto Rico Travel Health Guide
Low risk
Puerto Rico carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
Overall risk
Low risk
Malaria
None
Best time to visit
Year-round
Recommended vaccines
Routine Vaccines
Make sure you're up-to-date on all routine vaccines including chickenpox, tetanus, flu, MMR, polio, and shingles before traveling.
COVID-19
All eligible travelers should be up to date with their COVID-19 vaccines.
Hepatitis A
Hepatitis A vaccine is recommended for unvaccinated travelers to Puerto Rico. Infants 6-11 months should also get vaccinated.
Hepatitis B
Hepatitis B vaccine is recommended for all unvaccinated travelers to Puerto Rico.
Measles
Measles cases are rising worldwide. All travelers should be fully vaccinated with MMR vaccine, including infants 6-11 months who need an early dose.
Typhoid
Typhoid vaccine is recommended for most travelers to Puerto Rico, especially if staying with friends/relatives or visiting smaller cities or rural areas.
Rabies
Rabies is not common in dogs in Puerto Rico but is found in wildlife and bats. Pre-exposure vaccination may be considered for high-risk activities. Post-exposure vaccines are available if needed.
Yellow Fever
Yellow fever vaccine is not recommended and not required for entry to Puerto Rico.
Disease risks
Emergency numbers
Police
911
Medical / Ambulance
911
Fire
911
Tourist Police
+1-787-977-1615
U.S. Embassy
+1-787-521-2000
More country guides
Anguilla carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
Antigua and Barbuda carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
Aruba carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B. Yellow fever vaccine is not needed for direct travel from the US, but required if coming from countries with yellow fever risk
Plan your Puerto Rico trip
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Build my Trip KitSources: CDC Travelers' Health · WHO International Travel and Health. Last updated 2026-07-31. Health conditions and entry rules change — verify with the CDC, WHO and your destination’s authorities before travel. This page is informational and not a substitute for advice from a travel-medicine provider.