Moderate riskEurope · Southern EuropeSpain Travel Health Guide
Moderate risk
Spain carries a CDC Level 2 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
Overall risk
Moderate risk
Malaria
None
Best time to visit
Year-round
Recommended vaccines
Routine Vaccines
Make sure you are up-to-date on all routine vaccines including chickenpox, DTP, flu, MMR, polio, and shingles before traveling.
COVID-19
Stay up to date with COVID-19 vaccines before traveling.
Hepatitis A
Consider hepatitis A vaccination, especially if visiting smaller cities, villages, rural areas, or planning to eat street food.
Hepatitis B
Hepatitis B vaccine is recommended for unvaccinated travelers under 60, and may be considered for those 60 and older.
Measles
Get fully vaccinated against measles with MMR vaccine at least two weeks before travel. Infants 6-11 months should receive an early dose.
Polio
Polio vaccination is important as poliovirus has been identified in Spain. Adults may need a booster, and unvaccinated travelers should complete the series before travel.
Rabies
Rabies pre-exposure vaccination may be considered for high-risk activities. Rabid dogs are uncommon in Spain and post-exposure vaccines are generally available.
Yellow Fever
Yellow fever vaccine is not recommended and not required for entry to Spain.
Disease risks
Emergency numbers
Police
112
Medical / Ambulance
112
Fire
112
U.S. Embassy
+34-91-587-2200
More country guides
AlbaniaLow riskAlbania carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B. Yellow fever vaccine is not needed for direct travel from the US, but is required if coming from countries with yellow fever risk.
AndorraLow riskAndorra carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis B, Measles.
Bosnia and HerzegovinaLow riskBosnia and Herzegovina carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
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Build my Trip KitSources: CDC Travelers' Health · WHO International Travel and Health. Last updated 2026-07-31. Health conditions and entry rules change — verify with the CDC, WHO and your destination’s authorities before travel. This page is informational and not a substitute for advice from a travel-medicine provider.