Permit RequiredNarcotic · Ketamine

Is Ketamine Legal in Japan?

Reviewed by Dr. Lo and Dr. Lee (PharmD)·Last updated

NCD permit required

Ketamine and esketamine (Spravato) are narcotics in Japan and require an NCD import permit. Telehealth ketamine prescriptions are increasingly common in the US for depression — these can be traveled with only with the NCD permit, not the US prescription alone.

Japan status

Permit Required

Quantity threshold

Not applicable

Substance class

Narcotic

Why is Ketamine controlled in Japan?

Ketamine is classified as a narcotic under Japan's Narcotics and Psychotropics Control Law.

How to apply for the NCD import permit

  1. 1Apply for the NCD import permit at least 14 days before your arrival date.
  2. 2Doctor's letter (dated within 3 months) must list: your full name, diagnosis, medical necessity, drug name, strength, daily dose, and the prescribing doctor's signature.
  3. 3Attach photos of original packaging showing drug name and strength.
  4. 4You must carry the import certificate with you and present it at customs — not in checked baggage.

Application form: Submit through the Japan Narcotics Control Department (NCD).

NCD import permit application

Frequently asked questions

Can I bring Spravato for depression to Japan?

Spravato (esketamine) administration in the US is typically clinic-supervised, not take-home. If you have take-home doses, you need an NCD permit. Coordinate with your prescriber and consider a treatment gap rather than travel.

Related medications

Check your full travel kit

Ketamine is just one medication — most travelers carry several. Our free checker reviews your entire prescription list against Japan’s import rules.

Check all my medications

Source: MHLW Narcotics Control Department — Controlled Substances List (12 Dec 2024). Page last reviewed 2026-05-31 by Dr. Lo and Dr. Lee (PharmD). Regulations change — verify with the MHLW Narcotics Control Department before travel. This page is for informational purposes and is not a substitute for advice from your prescribing physician or from a Japanese customs authority.